Consolidating the service sector as the driver of economic growth in Luxembourg is a national priority. Research should primarily contribute to maintain the international competitive position of Luxembourg’s financial industry and the attractiveness of Luxembourg as a market place. This should also help diversifying the Luxembourg economy and ensuring the long-term economic sustainability. Research should lend momentum to the development of new high-value added services - for both business and the general public - and the improvement of Luxembourg’s innovation capacity. The challenge here is to develop the best framework for innovation and to improve the ICT infrastructure, as well as information security and trust management in e-applications to provide a good basis for developing new niches for economic development.